Discuss “CMU neurobiologist discovers a novel treatment for seizures”
Alison Barth, assistant professor of biological sciences at Carnegie Mellon University, received a $50,000 grant from the Milken Family Foundation to further her research on a novel treatment for seizures. A drug that acts on a single ion channel is the key to this new treatment, which she hopes will one day be used to prevent seizures in children.
Barth’s research identified a specific neuronal target that, when blocked with the drug, significantly reduced seizure occurrence and frequency in vitro. The real surprise came when she made the switch from in vitro to in vivo, testing the drug within a living organism and finding that it worked very well.
The target in question is an ion channel, a structure through which ions, or charged atoms,...
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